Endocrine Abstracts

Hirsutism is an endocrine condition affecting females with growth of unwanted, male-pattern hair secondary to excess androgen activity. The most common cause of hirsutism in females is PCOS (Polycystic ovarian syndrome). Other causes are fairly rare including adrenal and ovarian androgen producing tumours. In 3% of cases no cause of hirsutism is found and these are termed idiopathic1. We describe a unique case of a 22-year-old presenting w...

A 74 years old man prsented with gradually worsening confusion with associated jerky movements with background of well controlled type 2 Diabetes, CKD-3, IHD and previous duodenal ulcer. His was on Finasteride, Omeprazole, Mirtazapine, Tamsulocin, Metformin, Atorvastatin, Humulin I insulin. He was taking omeprazole for Duodenal ulcer since 1993.On examination he had jerky movements of the arms suggestive of muscles spasms. Res...

Teddy is a highly proliferative goat breed, as females of this breed are famous for high twinning rates. Feed supplementation of olive oil has been shown to improve semen quality of goat bucks. In this study, the effects of feed supplementation with olive oil on serum testosterone, triiodothyronine (T3), thyroxine (T4) and some biochemical metabolites in Teddy goat bucks were investigated. For this purpose, 9 adult male goats, with clinically normal reproduc...

Moyamoya disease is a progressive chronic neurological disease due to multiple narrowing of the carotid arteries. It can be seen in association with atherosclerosis, vasculitis, haematological conditions, connective tissue disease, neurocutaneous syndromes and certain autoimmune diseases. Very few cases have been reported in association with Graves disease and the majority being in the East Asian population. We present a rare case of this association in a young C...

Hirsutism is an endocrine condition affecting females with growth of unwanted, male-pattern hair secondary to excess androgen activity. The most common cause of hirsutism in females is PCOS (Polycystic ovarian syndrome). Other causes are fairly rare including adrenal and ovarian androgen producing tumours. In 3% of cases no cause of hirsutism is found and these are termed idiopathic1. We describe a unique case of a 22-year-old presenting w...

Background: Patients with adrenal incidentaloma (AI) and cortisol levels of 50-138 nmol/l on overnight dexamethasone suppression tests (ONDST) may have “mild autonomous cortisol secretion” (MACS). MACS is associated with increased morbidity, including osteoporosis, but this is infrequently systematically evaluated. We compared fracture risk and fracture prevalence in patients with AI, both with and without MACS.Methods: Data were collected retr...

Background: Maturity-onset diabetes of the young (MODY) is a group of 13 monogenic forms of diabetes transmitted in an autosomal dominant pattern and is characterized by a primary defect in pancreatic β-cell function. This disease has an early onset, usually before 25 years of age. It may present with mild asymptomatic hyperglycemia with progressive development to clinical diabetes mellitus. First-line treatment relies on sulphonylureas or insulin according to MODY subtyp...

Introduction: Commonest causes of pancreatitis are alcohol and gallstones but less common causes like hypertriglyceridemia should also be considered as management may differ.Case history: 47 years old gentleman with history of pancreatitis and hyperlipidaemia type1 taking atorvastatin and bezafibrate, admitted with severe abdominal pain and vomiting. He was non-smoker and non-drinker. No history of cholelithiasis or medications causing pancreatitis. He w...

Section 1: Case history: A 66-year-old man, with a history of hypertension controlled on 3 anti-hypertensives and diet-controlled Type 2 Diabetes, presented to a community-based musculoskeletal clinic to have an intra-articular Triamcinolone injection for a frozen shoulder. 30 min after the injection, he developed dyspnoea, widespread urticaria and facial angioedema. He was initially treated for suspected anaphylaxis with adrenaline, antihistamine and Hydrocortisone at the GP ...

Introduction: We describe the case of a patient referred to Cardiology with an abnormal ECG & hypertension. Investigation led to the diagnosis of catecholamine induced cardiomyopathy caused by a pheochromocytoma. The case is unique as the cardiomyopathy was reversed with alpha and beta blockade prior to surgery.Case: A 56 year old female with 20 pack year smoking history, no regular medications and evidence of hypertension underwent CT AP for abdomin...